Santa Ana is the most populous city in Orange County, California and is the county seat. It lies approximately 10 miles inland from the Pacific Ocean, on the largely seasonal Santa Ana River. The Santa Ana Freeway (Interstate 5) runs through the city, and the Costa Mesa Freeway (55 Freeway) and Garden Grove Freeway (22 Freeway) travel along its edges. It is today best-known for its enormous Hispanic population, now comprising over 75% of what was once a virtually all-white city. It has the highest percentage of Latinos among the 50 largest cities in America. The Current OMB metropolitan designation for Santa Ana and the Orange County Area is Santa Ana-Anaheim-Irvine, CA.